• A data mining approach for classification of orthostatic and essential tremor based on MRI‐derived brain volume and cortical thickness 

      Benito-León, Julián; Louis, Elan D.; Mato-Abad, Virginia; Sánchez‐Ferro, Alvaro; Romero, Juan Pablo; Matarazzo, Michele; Serrano, J. Ignacio (John Wiley & Sons Ltd., 2019-11-26)
      [Abstract] Objective - Orthostatic tremor (OT) is an extremely rare, misdiagnosed, and underdiagnosed disorder affecting adults in midlife. There is debate as to whether it is a different condition or a variant of essential ...
    • Assessment of Tremor Severity in Patients with Essential Tremor Using Smartwatches 

      Velasco, Miguel A.; López-Blanco, Roberto; Romero, Juan Pablo; Castillo-Sobrino, Mª Dolores del; Serrano Moreno, José Ignacio; Benito-León, Julián; Rocón, Eduardo (Servicio de Publicaciones de la Universidad de Oviedo, 2017)
      [Abstract] This paper presents a classification model for the automatic quantification of tremor severity in patients with essential tremor (ET). The system is based on the signals measured by two commercial smartwatches ...
    • Classification of Radiologically Isolated Syndrome and Clinically Isolated Syndrome with Machine-Learning Techniques 

      Mato-Abad, Virginia; Labiano-Fontcuberta, Andrés; Rodríguez-Yáñez, Santiago; García-Vázquez, Rafael; Munteanu, Cristian-Robert; Andrade-Garda, Javier; Domingo-Santos, Ángela; Galán Sánchez-Seco, Victoria; Aladro, Yolanda; Martínez-Ginés, Mª Luisa; Ayuso, Lucía; Benito-León, Julián (2019)
      [Abstract]: Introduction: The unanticipated magnetic resonance imaging (MRI) detection in the brain of asymptomatic subjects of white matter lesions suggestive of multiple sclerosis (MS) has been named as radiologically ...
    • Diffusion tensor imaging in orthostatic tremor: a tract‐based spatial statistics study 

      Benito-León, Julián; Romero, Juan Pablo; Louis, Elan D.; Sánchez‐Ferro, Alvaro; Matarazzo, Michele; Molina‐Arjona, José A.; Mato-Abad, Virginia (John Wiley & Sons Ltd., 2019-10-06)
      [Abstract] Objective The pathogenesis of orthostatic tremor (OT) is unknown. We investigated OT‐related white matter changes and their correlations with scores from a neuropsychological testing battery. Methods Diffusion ...
    • White matter microstructural changes are related to cognitive dysfunction in essential tremor 

      Benito-León, Julián; Mato-Abad, Virginia; Louis, Elan D.; Hernández-Tamames, Juan Antonio; Álvarez-Linera, Juan; Bermejo-Pareja, Félix; Domingo-Santos, Ángela; Collado, Luis; Romero, Juan Pablo (Nature Research, 2017-06-07)
      [Abstract]: Diffusion tensor imaging (DTI) studies have detected white matter microstructural changes in essential tremor (ET). However, it is still unclear whether these changes are related to cognitive deficits, which ...